Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study

STRENGTHS AND LIMITATIONS OF THIS STUDY The strengths of the study include the use of real-world…

Community-based interventions to prevent stroke in low-income and middle-income countries: a protocol for a systematic review and meta-analysis

Introduction Globally, stroke is considered the second leading cause of death after ischaemic heart disease though…

Navigating the river(s) of systems change: a multi-methods, qualitative evaluation exploring the implementation of a systems approach to physical activity in Gloucestershire, England

Introduction Global data suggest that a quarter of adults and three-quarters of adolescents do not engage…

Seroprevalence of syphilis and its predictors among pregnant women in Buno Bedele zone, southwest Ethiopia: a community-based cross-sectional study

STRENGTHS AND LIMITATIONS OF THIS STUDY This study used a stratified multistage random sampling method with…

Use of a penicillin allergy clinical decision rule to enable direct oral penicillin provocation: an international multicentre randomised control trial in an adult population (PALACE): study protocol

A 6-month postrandomisation telephone questionnaire, based on previous publications,11 will help assess the impact of outpatient…

PREPARE trial: a protocol for a multicentre randomised trial of frailty-focused preoperative exercise to decrease postoperative complication rates and disability scores

Introduction Rates of major surgery are growing most rapidly in older people.1 Frailty, a multidimensional state…

Clinical presentation in EMS patients with acute chest pain in relation to sex, age and medical history: prospective cohort study

Strengths and limitations of this study The unselected inclusion of a close to complete county population…

Factors influencing the safety of outpatient coronary CT angiography: a clinical registry study

Strengths and limitations of this study The study includes a large population of real-world patients and,…

Educational inequalities in adult mortality: a systematic review and meta-analysis of the Asia Pacific region

Strengths and limitations of this study The present study provides the most up-to-date collection of evidence…

Experiences of patients with multimorbidity with primary care and the association with patient activation: a cross-sectional study in Germany

Strengths and limitations of this study Patients with various combinations of chronic diseases were surveyed in…