Introduction The increased prevalence of mental health conditions as a consequence of the COVID-19 pandemic1 and…
Category: Clinical News
Human umbilical cord mesenchymal stem cell therapy for renal dysfunction in Alport syndrome: protocol for an open-label, single-arm trial in China
Introduction Alport syndrome (AS) is one of the most common human fatal hereditary renal diseases. Its…
Multicentre, randomised, double-blind, placebo-controlled, proof of concept study of LSALT peptide as prevention of acute respiratory distress syndrome and acute kidney injury in patients infected with SARS-CoV-2 (COVID-19)
Strengths and limitations of this study Phase 2 randomised double-blind placebo-controlled multi-centre design. International study cohort…
Adjuvant chemotherapy and survival outcomes in older women with HR+/HER2- breast cancer: a propensity score-matched retrospective cohort study using the SEER database
Introduction Along with the increase in population ageing, the incidence of breast cancer (BC) in older…
Experiences, prevalence and drivers of disrespect and abuse of adolescents during facility-based childbirth in sub-Saharan Africa: a scoping review protocol
Introduction Disrespect and abuse (D&A) of women by skilled health personnel during facility-based childbirth is a…
Defining acceptable data collection and reuse standards for queer artificial intelligence research in mental health: protocol for the online PARQAIR-MH Delphi study
The multistage consensus method will follow recommendations for the Delphi technique.50 The fundamental principles of Delphi…
How to facilitate NHS professionals to recognise and use skills gained from global health engagement when back in the UK workforce? A participatory action research project to design, pilot and evaluate a series of online leadership workshops
Strengths and limitations of this study The study used a participatory action research approach, which ensured…
Prevalence and predictors of depression and anxiety in patients with chronic rhinosinusitis: a systematic review and meta-analysis
STRENGTHS AND LIMITATIONS OF THIS STUDY The research samples were drawn from four continents, demonstrating racial…
IMPROVE study protocol, investigating post-stroke local muscle vibrations to promote cerebral plasticity and functional recovery: a single-blind randomised controlled trial
Introduction Stroke is one of the most common neurological disorders worldwide, affecting about 12 million people every…
Impact of chronic oral glucocorticoid treatment on mortality in patients with COVID-19: analysis of a population-based cohort
STRENGTHS AND LIMITATIONS OF THIS STUDY Uses a population-based design. Employs adjusted Cox models and propensity…