Low back pain management in primary healthcare: findings from a scoping review on models of care


  • To the best of our knowledge, this is the first study aiming to map the available evidence regarding the core characteristics and key elements of models of care (MoCs) implemented in primary healthcare for the management of low back pain (LBP).

  • To aid the transparency and methodological rigour of this study, it followed the Joanna Briggs Institute Methodological Guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews.

  • One limitation of this review is potential selection bias due to search strategies and language restrictions, as well as heterogeneity in MoC terminologies.

  • Strategies to overcome potential limitations included the use of a broad search strategy across databases, an overinclusion approach during article screening and regular team discussions during data extraction and analysis.

  • This study offers a comprehensive understanding of key characteristics of the MoCs implemented for LBP patients in primary healthcare, which may help clinicians and decision-makers to plan the implementation of MoCs in real-world settings, as well as researchers defining avenues to overcome the current evidence-to-practice gaps.


Low back pain (LBP) is a significant global public health concern, acknowledged as the leading contributor to disability worldwide. In 2020, 619 million (95% Uncertainty Interval (UI) 554 to 694) people reported having this health condition and prevalence projections suggest it will escalate to 843 million (95% UI 759 to 933) by 2050, an increase in total cases of 36.4%.1 It is recognised that the burdensomeness of LBP is related to long-term disability and poor health-related quality of life,2–4 associated with more medical costs and utilisation of healthcare resources, such as medication, medical appointments, imaging and physiotherapy.2 5–7 Thus, LBP represents a growing burden for individuals, society and healthcare systems.

Although care delivery may vary between health systems, primary healthcare is recognised as the appropriate setting to manage LBP,8 9 which is already one of the most common reasons for general practice consultations worldwide.8 10 Accompanying the estimates of the rising prevalence of LBP, it is also expected a significant increase in primary healthcare workload in the upcoming years,9 so there is an urgent need to develop efficient and sustainable solutions to face these healthcare challenges.

Additionally, evidence shows there is a present gap between the recommended practice for LBP and the care provided in real-world contexts.9 Current patterns of care may vary between settings and lack alignment with clinical practice guideline recommendations, which succinctly endorse the delivery of non-pharmacological interventions, such as education and exercise, and manual therapy as an adjuvant treatment.8 11–14 However, many LBP patients receive unnecessary low-value care, which does not align with quality standards,14 15 leads to poor clinical outcomes4 16 and wastes healthcare resources.17–19 Therefore, system-level reform strategies are necessary to overcome these evidence-to-practice gaps and to promote the delivery of high-quality care to LBP patients.9 17 20

The implementation of models of care (MoCs) is one of the most promising strategies suggested to increase the responsiveness of health systems to the impact of LBP. A MoC is a person-centred approach that outlines evidence-informed best practices for managing specific health conditions.21–23 It details the optimal care that should be provided and the methods for its implementation. MoCs are built on clinical guidelines—drawing from up-to-date recommendations—and they primarily serve to translate these recommendations into actionable strategies.23 While clinical pathways focus on the integrated delivery of care to patients with a specific condition, MoCs go beyond this aspect, focusing much of their attention on the factors that determine a successful implementation.22 23

The principles of MoCs are in line with the quadruple aim of value-based care, targeting better health outcomes, better patient and health professional experiences and improved use of healthcare resources.17 21 MoCs usually reflect regional or national health policies that are implemented as health services in local settings.22 24 When implemented locally, a MoC includes the key core components from the system-level framework, but other elements should be adapted to meet the specific context and needs.17 The operationalisation of a MoC for local service delivery is usually designated as a model of service delivery.17

Several MoCs have been implemented for LBP patients over the last few years in different countries. Commonly, these MoCs deliver care through stepped or stratified approaches, supporting the decision-making process. In stepped care, all patients are initially offered the same treatment options and more complex care is only proposed if they have not recovered sufficiently, while, in risk-stratified MoCs, patients are stratified according to their prognosis at initial assessment and treatment is targeted to patient subgroups, with more comprehensive care offered to those at risk of poor outcomes.25

Although some MoCs reveal promising results regarding their effectiveness and cost-effectiveness,9 23 they are very heterogeneous in terms of their characteristics, making it difficult to assess the suitability of a MoC to a given context over another. These characteristics include but are not limited to, the target population, clinical pathways, levels of care and health professionals involved, type of care (stepped/stratified approaches), health interventions and context features.

Two recent reviews26 27 have analysed the evidence on initiatives for implementing LBP management. One review focuses specifically on MoCs implemented in Australia.26 The other, a systematic review,27 aims to describe clinical pathways and care integration across different levels of care, without focusing on the details of care delivery and implementation. Therefore, our work seeks to expand on these contributions by providing a broader overview of the diversity, content and resource requirements of MoCs for LBP patients. This is important information to support policy-makers, managers, clinicians in the development and implementation planning of MoCs, as well as pinpoint evidence gaps related to implementation in real-world settings.


A scoping review was deemed the most appropriate study design to answer the research questions as it aims to map the available evidence and identify characteristics or factors related to an emerging and complex concept.28 29 The uncertainty regarding the evidence sources, methodologies and amount and quality of available data determined the choice of this approach.

This study was conducted in accordance with the Joanna Briggs Institute (JBI) scoping review guidance and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA) (online supplemental file 1). The protocol was registered within the Open Science Framework Registries (https://osf.io/rsd8x) and it was published elsewhere.30

Supplemental material

Patient and public involvement

Patients and public were not included in the design, conduct or reporting of this research as it is targeted at researchers, clinicians, managers and policy-makers.

Research question and aims

The research question of this review is ‘What are the key characteristics of MoCs implemented in primary healthcare for patients with LBP?’ Our objectives are to identify which MoCs have been implemented for LBP management, describe their main characteristics and similarities in care delivery, and highlight any gaps in knowledge regarding their real-world implementation.

Inclusion criteria

Eligibility criteria were defined through the Population, Concept, Context framework.28 29 The target population are LBP patients, with or without radicular pain, of any duration, excluding specific causes or serious pathologies. Records including broader populations, such as ‘musculoskeletal pain’ or ‘spinal pain’, were also excluded. MoC was defined as the provision and delivery of care in a local setting, including service planning, care coordination and management of services.21 22 31 Operational criteria were defined to differentiate a MoC from intervention programmes.22 30 Regarding the context, MoCs were included if they were developed in primary healthcare or other levels of healthcare delivery, as long as they included primary care interventions in the clinical pathway.31

Search strategy

A comprehensive search was conducted on MEDLINE (PubMed), EMBASE, Cochrane Central Register of Controlled Trials, PEDro, Scopus and Web of Science, as well as grey literature sources (figure 1). Handsearching was performed in peer-reviewed journals and relevant organisation websites.32 Additional studies were identified through reference list screening. Initial searches conducted in May 2021 used key terms such as “low back pain,” “model of care” and “primary care”. Subsequent tailored searches across all databases were performed (online supplemental file 2). Only records published since 2000 were considered as we aim to examine evidence-based and coordinated healthcare delivery for LBP, reflecting the current concept of MoC. Language restrictions for English, Portuguese or Spanish were established due to practical constraints related to the availability of translation resources. The search commenced in January 2022 and was last updated in December 2022, with search strategies reviewed and conducted by an experienced information scientist (HD).

Supplemental material

Figure 1
Figure 1

PRISMA flow diagram showing the identification, screening, eligibility and inclusion process of the articles. LBP, low back pain; MoCs, models of care; PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses.

Study selection

Records were imported to EndNote V.X9 (Clarivate Analytics, USA) for screening and duplicate removal. Two reviewers independently screened titles and abstracts (STD and DC). Eligibility criteria were tested with a random sample of 25 records. Afterwards, full-text screening was performed by two researchers (STD and AM), with a pilot test on 10 studies for consistency. Disagreements were discussed with a third reviewer (DC).

Data charting

To ensure data extraction transparency,28 a standardised form (online supplemental file 3) was developed and piloted, covering a summary of the studies, the identification and description of the MoC (name, country, target population and main objectives) and respective key elements (levels of care and settings, health professionals involved, type of care delivered and core components of health interventions). Two researchers (STD and AM) extracted data independently and resolved uncertainties with the research team. Only relevant data to the research question were extracted, and when necessary, the authors were contacted for clarification. Regular video meetings were held for data review and process updates.

Supplemental material

Synthesis and presentation of results

Findings were synthesised through deductive content analysis in three phases: preparation, organisation and reporting.33 Data are presented in narrative, tabular and chart formats for each MoC for LBP management. Descriptive results include the identification of the MoCs, their general description and key elements while quantitative results refer to frequency counts of the data.

Protocol deviations

Four research questions were framed in the protocol of this study.30 However, during the processes of data extraction and analysis, it became clear that the complexity of the topic and richness of the available data justified a rigorous description and interpretation of the findings. Therefore, findings on patient-related, system-related and implementation-related outcomes of MoCs and context-specific factors (macro, meso, micro and multiple levels) contemplated in their implementation will be reported in a subsequent paper. Additionally, one criterion was added to those published in the protocol, which is the MoC is not digital (eg, telemedicine, telerehabilitation, web-based programmes and/or mobile apps).


Search results

The PRISMA flow diagram (figure 1) outlines the search and selection process. From the 4081 records yielded in first instance, 29 studies,34–62 published between 2011 and 2022, were included. They portray 11 MoCs implemented in primary healthcare.

Characteristics of the included studies

Table 1 identifies each MoC and their corresponding studies. Quantitative studies (n=19) mainly consisted of randomised controlled trials (n=9) and observational cohorts (n=9). These studies assessed the clinical effectiveness and efficacy of nine MoCs34 39 42 44 46 48 49 51 55 57 58 60–62 and healthcare resources utilisation of seven MoCs.34 39 46 52–54 56–58 60–62 Only BetterBack☺ was evaluated for healthcare quality43 and economic evaluations were solely performed for three MoCs.34 35 46 58 60 61 Qualitative studies (n=5; 5 MoCs) focused on implementation outcomes and strategies36 37 41 45 59 while mixed-methods studies (n=5; 3 MoCs) investigated patient and organisational outcomes, as well as the experiences of different stakeholders.38 47 50 Detailed characteristics of the studies, including eligibility criteria, sample sizes, outcomes and outcome measures, can be found in online supplemental file 4.

Supplemental material

Table 1

MoCs identification and corresponding studies

General description

The 11 MoCs implemented in primary healthcare for the management of LBP patients are the STarT Back,34 35 46 56–58 SCOPiC,59–61 MATCH,36 62 TARGET,37–39 BetterBack☺ MoC,40–43 Low Back and Radicular Pain Pathway,44 45 47–49 Beating Back Pain Service (BBPS),50 North East Essex Primary Care Trust (PCT) manual therapy service,51 Interprofessional Spine Assessment and Education Clinics (ISAEC),52 Saskatchewan Spine Pathway (SSP)53 54 and Back Pain Assessment Clinic (BAC).55

All MoCs were implemented in high-income countries from Europe, North America and Australia (figure 2). Most implementations (n=5) were set in the UK, followed by the USA (n=2) and Canada (n=2). STarT Back34 35 46 56–58 was the only MoC implemented in three countries (the UK, Ireland and Denmark). However, adaptations of this MoC, with significant adjustments to its core characteristics, were also implemented in the USA (MATCH and TARGET)36–39 62 and Sweden (BetterBack☺).40–43

Figure 2
Figure 2

Geographical representation of the MoCs (n=11) implemented for LBP in primary healthcare worldwide. LBP, low back pain; MoCs, models of care.

The target population of the MoCs involved adults with LBP, with or without radicular pain, or radiculopathy. North East Essex PCT manual therapy service51 and BAC55 also included patients with neck pain. BBPS50 and Irish STarT Back57 were the only MoCs that established the duration of pain as an eligibility criterion, namely, the presence of LBP for more than 6 weeks and 3 months, respectively (online supplemental file 4).

Most MoCs (n=8) aimed to promote evidence-informed practice to improve clinical effectiveness. They were informed by national or international clinical practice guidelines to design the service delivery and health interventions for the management of LBP. Only Canadian MoCs, ISAEC52 and SSP,53 54 did not specify the guidelines they followed, although the studies mentioned the need to provide care in line with current recommendations.

MoCs comprising more than one level of care, such as interface services and/or secondary care,44 45 48 49 52–55 59–61 were especially concerned with reducing waiting times and optimising referral behaviours for imaging, care delivery and specialist review. Goals related to equitable access to care were only identified for the LBP and Radicular Pain Pathway44 and the North East Essex PCT manual therapy service.51

The majority of MoCs were implemented within the National Healthcare Systems through local (n=3) and regional (n=7) pathways. Only the LBP and Radicular Pain Pathway refers to a national MoC44 45. MATCH36 62 and TARGET37–39 were implemented in integrated healthcare delivery systems of the USA. Additionally, only four MoCs (Danish STarT Back, SCOPiC, TARGET and ISAEC)39 52 58 60 were implemented in different geographical areas, covering urban, inner city and rural settings.

Table 2 presents detailed information on the general characteristics of the different MoCs, including target population, goals, type of care, settings and health professionals involved in care delivery.

Table 2

General characteristics of the MoCs

Settings and healthcare professionals

Most MoCs (n=10) for LBP encompass multiple healthcare setting. General practices serve as the entry point for eight MoCs, being important in the initial management of LBP patients. These MoCs ensure continuity of care in outpatient physiotherapy clinics and community care settings, where patients receive the main health interventions. SCOPiC,59–61 Low Back and Radicular Pain Pathway44 45 47–49 and BAC55 also include other settings, such as interface, secondary and tertiary care services. MATCH,36 62 TARGET37–39 and BetterBack☺40–43 were exclusively implemented in primary healthcare clinics featuring onsite physiotherapy departments.

The health professionals who most commonly deliver care in MoCs are general practitioners and physiotherapists. General practitioners are primarily involved in the initial assessment and referral of patients receiving health services, whereas physiotherapists oversee the rehabilitation process. Four models also include osteopaths, chiropractors and acupuncturists,44 45 50–52 depending on the integration of these professionals within the specific healthcare system of each country. MoCs that incorporate more than one level of care44 45 53–55 59–61 comprise consultations of medical specialties with surgeons and rheumatologists. Four MoCs44 45 47–49 52–54 59–61 also include advanced practice clinicians, usually physiotherapists specialised in triage processes and identification and management of red flags and emergency conditions.

Type of care

The majority of MoCs (n=7) use a stratified care approach, targeting health intervention to patients’ subgroups based on their prognostic profile and/or pattern diagnosis. Less treatment is given to those who are at low risk or whose signs and symptoms are less severe while high-risk patients receive more specialised treatment or are referred to secondary care. The only MoC that is characterised by a stepped approach is the BAC,55 being essentially a health service dedicated to the screening and referral of LBP patients.

Hybrid care, combining stratified and stepped approaches, was identified in four MoCs. BetterBack☺40–43 and Low Back and Radicular Pain Pathway44 45 47–49 stratify patients based on clinical prognosis. If there are no improvements after the main health intervention, patients are referred to additional group care in BetterBack☺40–43 and to Pain Management Services and specialist spinal surgical options in the Low Back and Radicular Pain Pathway.44 45 47–49 In BBPS50 and North East Essex PCT service,51 the stepped care occurs first through education sessions and usual general practitioner care, respectively. Patients are stratified a posteriori based on their treatment preferences, such as care provided by physiotherapists, osteopaths or chiropractors. Figure 3 and table 2 summarise the type of care provided in each MoC.

Figure 3
Figure 3

Sunburst chart representing the different approaches of care delivered by the MoCs. BAC, Back Pain Assessment Clinic; BBPS, Beating Back Pain Service; ISAEC, Interprofessional Spine Assessment and Education Clinics; MoCs, models of care; PCT, Primary Care Trust; SCOPIC, Sciatica Outcomes in Primary Care; SSP, Saskatchewan Spine Pathway.

Core components of MoCs

To facilitate the reporting, core components were separated into five moments, which correspond to referral, assessment, health interventions, follow-ups and discharge. These elements are presented in online supplemental file 5.

Supplemental material

Referral and assessment

As aforementioned, the initial consultation with a general practitioner is an entry point on the pathway in all MoCs. In three MoCs,34 35 40–45 self-referral through direct access to services is possible, as well as a referral by other health professionals (MATCH, TARGET and ISAEC). Surgeons are the main referrers in SSP53 54 and BAC.55

The assessment of LBP patients concerns mainly the exclusion of red flags, physical assessment and stratification. Physiotherapists are the most common health professionals (n=9) to carry out the assessment, followed by the GP and triage specialists. The only model that does not carry out an assessment before an intervention is the BBPS,50 which is only performed after a group education session.

Health interventions

Education (n=10), exercise (n=9) and manual therapy (n=7) were the key core elements of MoCs reported by most studies. With the exception of North East Essex PCT service51 and BAC,55 all MoCs included at least a minimal education intervention, focusing on the reassurance about the benign nature of LBP and self-management strategies. These messages were communicated directly by the health professionals or through support tools, such as written information, DVDs and online content.

In MoCs that include a stratified approach, patients receive appropriate matched treatments, with different doses of education, exercise and manual therapy, according to their prognosis, pattern diagnosis or treatment preference. More complex interventions, such as interventions for high-risk patients34–41 43 45 46 48 56–58 60 62 and community-based spinal rehabilitation programmes,44 45 47–49 55 combine physical and psychological therapies, adding cognitive-behavioural approaches and support for long-term self-management. However, these are poorly described in the included studies.

The majority of MoCs include a health intervention that may vary from a single session (for low-risk patients in stratified approaches according to prognosis profile) to several weeks of multifaceted rehabilitation programmes. However, not all models establish a specific duration for these interventions. Individualised treatments are the chosen format for healthcare delivery in most MoCs, except for Irish STarT Back.57 Group interventions appear to be a second treatment option in BetterBack☺40–43 and Low Back and Radicular Pain Pathway44 45 47–49 when the main health intervention did not result in benefits for LBP patients.

Other interventions, such pain medication prescription or review, were usually delivered by GP or other medical doctor in the initial consultation (STarT Back, TARGET, Low Back and Radicular Pain Pathway and SSP). None of the MoCs included occupational interventions or treatments focused on the adoption of healthy lifestyles.

Follow-up and discharge

Follow-up management and criteria for discharge were not well-defined in the included studies. When there are no improvements in the health condition, follow-ups may combine referral to additional group interventions, interface or secondary/tertiary care services. Irish57 and Danish58 STarT Back, TARGET37–39 and BBPS55 did not report how and when follow-ups are conducted.

Concerning discharges, it seems they occur at the end of health interventions, but the reporting is not clear. In risk-stratified models, such as STarT Back, patients attend a preset number of appointments to receive treatments. However, it is poorly described if patients are discharged after this period, with six MoCs not mentioning any criteria or timing. In TARGET,37–39 Low Back and Radicular Pain Pathway44 45 47–49 and North East Essex PCT service51 patients can be discharged at any point along the pathway on improvement of the LBP.


This study mapped the available evidence regarding the core characteristics and key elements of MoCs implemented in primary healthcare for the management of LBP. 11 MoCs were found, all of them implemented in high-income countries with strong primary healthcare services, where general practitioners and physiotherapists serve as the main referrers. The majority of MoCs involve complex interventions delivered by physiotherapists, showing great variability in the reporting of core components, including unclear duration, follow-up and discharge criteria.

First, MoCs for LBP are in various stages of research and integration into health systems. While the LBP and Radicular Pain Pathway44 45 are implemented nationwide, other MoCs are in trial phases regionally or locally. This reflects a growing emphasis on adopting MoCs for LBP, recognised for their potential to enhance care quality through evidence-based practices.63 However, given the inconsistent outcomes observed with these MoCs, they are not yet suitable for implementation beyond research environments.

Recent studies show that LBP patients receiving treatments aligned with guidelines see better clinical outcomes and less healthcare usage.64 Although the reviewed MoCs align with these guidelines, only BetterBack☺40–43 65 has been assessed for its adherence to quality standards in care delivery. The reports suggest guideline-compliant designs, yet often lack detail on ensuring the intended delivery of interventions. The gap between research findings and practical application in clinical settings remains,9 66 as the current evidence does not fully explore this transition. Future research should more thoroughly document care delivery assessment and monitoring processes.

Ten MoCs included stratified care approaches. Considering the successful implementation of the STarT Back34 in the UK on clinical and cost-effectiveness,34 35 46 56 adaptations of this MoC were developed in other countries. Recently, a systematic review found that a stratified care approach provides substantial clinical, economic and health-related cost benefits in the medium and high-risk subgroups compared with usual care in short-term and medium-term follow-ups.67 This may explain why MoCs tend to follow a stratified or hybrid approach to deliver care using the STarT Back Screening Tool. However, evidence shows that some adaptations of the MoC in other countries, such as in the USA, failed to show its clinical effectiveness. Moreover, despite there being no current evidence favouring stratified over stepped approaches for LBP management, the stepped care has demonstrated efficacy for other musculoskeletal conditions, such as osteoarthritis.25 The development of future MoCs may involve research on stepped care solutions as both strategies are endorsed by guidelines for treating LBP.11 13 68 69

This review found that many MoCs for managing LBP align with recommended practices, emphasising primary and community care as initial contact points22 involving specialised health professionals, and focusing on education and exercise interventions.8 11–14 However, there was significant variability in how health interventions were reported over time, with many studies lacking detailed documentation on follow-up procedures, discharge criteria and specialised interventions across care levels. Accurate and detailed reporting of these interventions is essential for their replication and adaptation, critical for successful implementation in clinical settings.

MoCs aim to streamline and enhance healthcare efficiency through effective coordination across care sectors. Such coordination is key to delivering integrated, patient-centred care.17 22 Despite this emphasis, our review found that only 436–38 45 47 48 60 61 of the 11 MoCs provided clear details on achieving this coordination, often only mentioning clinical pathways and electronic health records. This gap suggests a potential underprioritisation of or challenges in implementing effective care integration, echoing broader findings of limited care integration for LBP patients between primary and secondary settings.27 70 Future research should focus on detailing strategies to improve healthcare provider collaboration, shared decision-making and treatment plan adjustments to foster better care integration.71

This review intended to inform clinicians and decision-makers on the current stage of MoCs implementation worldwide. We intend to continue this reflection through the synthesis of context-specific factors and outcomes used to evaluate the implementation of MoCs for LBP in primary healthcare. A subsequent paper will provide a comprehensive understanding of how implementation processes and strategies may have influenced outcomes.

Strengths and limitations

The major strength includes adherence to JBI recommendations28 29 32 and ensuring a robust and systematic methodology, right from protocol design to the presentation of results. Critical aspects such as the development of the search strategy, screening of records by two independent reviewers and regular team discussions during data extraction and analysis were conducted under this guidance. However, the study also faced challenges such as potential evidence selection bias due to search strategies and language restrictions, possibly excluding some pertinent studies on MoCs. Variations in MoC terminologies in literature, the inclusive definition of MoC and the ambiguity between specific evidence-based interventions and MoCs posed additional issues. Despite a focus on LBP-related MoCs, other relevant studies concerning spinal disorders may have been missed. To mitigate these issues, a broad and sensitive search strategy, an overinclusion approach during screening, several adjustments to the extraction form and regular reviewer discussions were employed. Yet, the diversity in MoC reporting possibly led to the omission of certain information, even though specific frameworks and a continuously adapted data form were utilised to tackle this challenge.


Throughout this process, it became evident that most of the MoCs implemented for LBP in primary healthcare are still under investigation and require further testing to produce robust estimates of their effectiveness, as well as guidance for optimal implementation. Future research should focus on effectiveness-implementation studies with pragmatic designs to reproduce the challenges of implementing MoCs in real-world clinical settings, such as integration across care sectors and differences in funding models, context features and teams of healthcare providers.70

Additionally, in line with the recommendations for conducting scoping reviews,28 29 a quality or risk of bias assessment was not performed in this study. Systematic reviews and meta-analyses are needed to assess the methodological quality of the studies and provide stronger conclusions on their findings. This knowledge may contribute to inform health policies, interventions and infrastructures favouring the implementation of a MoC that promotes the delivery of high-quality care for LBP patients in the most efficient and sustainable way for health systems.

Finally, this scoping review sheds light on features shared by MoCs for LBP, offering a detailed insight into their foundations, content and resource requirements. However, the heterogeneity in reporting reveals the need for guidelines on the development and the implementation of MoCs. This guidance will facilitate their transferability and adaptation to primary healthcare settings.


This study provides a broad overview of the key common elements of eleven MoCs implemented for LBP patients in primary healthcare worldwide. These MoCs are aligned with clinical practice guideline recommendations. Primary healthcare is the entry point for patients into the health system and they are offered stratified care approaches, based on education, exercise and manual therapy. More complex interventions or referrals to secondary and tertiary care are feasible options when first approaches fail. However, most studies were very heterogeneous in reporting care coordination and its delivery over time. Additionally, most MoCs are not integrated into health systems and are still in the early stages of research. These findings highlight the need for guidelines to support the research, development and implementation of MoCs in real-world settings.

Data availability statement

Data sharing not applicable as no datasets generated and/or analysed for this study. All data relevant to the study are included in the article or uploaded as online supplemental information. Not applicable as no datasets were generated for this study. All relevant data were included in the article or as online supplemental file. Additional data are not available.

Ethics statements

Patient consent for publication

Ethics approval

As this study involves a secondary analysis of previously published data, ethical approval is not required.


The authors gratefully thank the late Professor Carla Nunes for considerable help and inspiration in the design and development of this study.

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