Luton and Dunstable University Hospital adopts geko device

Luton and Dunstable University Hospital is amongst the first in a growing number of NHS hospitals nationally, and the first in the South East, to deploy the innovative geko™ device for VTE prevention in immobile acute stroke patients who cannot be prescribed the current standard of care.

The Luton & Dunstable accredited stroke unit provides Hyper-acute (clot buster), Acute and Rehabilitation services to a catchment population of 750,000 people across Luton, Bedfordshire, Hertfordshire and Milton Keynes.

They are the regions designated hospital for Thrombolysis with close integration with the neurosurgical team at Queen’s Square Hospital, London and Addenbrookes Hospital, Cambridge for patients who require neurosurgical interventions, and the Vascular Unit at Bedford Hospital for patients requiring surgery to the neck blood vessels.

VTE remains a common and life-threatening complication in acute stroke, which is further exacerbated if patients are immobile for prolonged periods. In this circumstance NICE and the UK National Clinical Guidelines for Stroke both recommend intermittent pneumatic compression (IPC), a boot-like cuff that compresses the legs to move blood, as the primary method of mechanical VTE prevention (NICE NG89 2018)1. IPC is, however, not suitable for all patients, due to vascular disease, fragile skin, reaction to the cuff materials and patient intolerance, creating a significant unmet need.

In a clinical audit of 320 patients, Luton and Dunstable University Hospital quantified the number of acute stroke patients who could not be prescribed IPC. To this unmet need patient group they instead prescribed the geko™ device as an alternative mechanical intervention.  The watch-sized device increases blood flow via painless electrical pulses to the leg, at a rate equal to 60%2 of walking without a patient having to move – thereby preventing vascular complications associated with restricted mobility, a common risk for bed-bound stroke patients.

The audit results showed a 17% unmet need in all mechanical prophylaxis prescriptions, when the geko™ device was on service, and reported the need for an alternative mechanical prophylaxis intervention and the need to prescribe the geko™ as an alternative anti-stasis device. These findings are aligned to the IPC compliance findings reported by Roffe and Natarajan3, and the CLOTS3 study4 that reports that patients immediately contraindicated to IPC and patients who become intolerant of IPC could be exposed to a VTE risk of up to 8.7%. The L&D enhanced pathway now offers a meaningful alternative mechanical intervention.

Dr Lakshmanan Sekaran, Consultant Stroke Physician and Clinical Director at the Luton and Dunstable Hospital, said: “When treating acute stroke patients, VTE is a very real and present threat to their recovery. The Royal Stoke real-world data, which led us to consider the geko™ device, reinforced that whilst IPC and blood thinners are effective for most patients, a small but significant number are unable to tolerate these methods, leaving them at greater risk of blood clotting. Recognising the need to address this patient group, we embraced the opportunity to quantify our unmet need and determine the effectiveness of the geko™ device as an alternative mechanical intervention. The geko™ device is now in routine use across our stroke units, when IPC cannot be prescribed and ensures that all patients can now receive post-stroke VTE prevention.”

Bernard Ross, Founder and CEO of Sky, the parent company of Firstkind Ltd, said: “The willingness of Luton and Dunstable University Hospital to embrace a safe and effective innovation is hugely significant for acute stroke patients who might otherwise fall between the cracks when it comes to VTE prevention. They saw the potential for a non-invasive, non-pharmacological intervention to prevent VTE in patients contraindicated or unable to tolerate IPC. Introducing any change, however, requires leadership, energy and collaboration and I applaud their diligence in working to put NICE guidance (MTG19)5, which recommends the geko™ device, into clinical practice for better patient outcomes.”

NICE guidance (MTG19) recommends use of  the geko™ device for VTE prophylaxis in all hospital patients where standard prophylaxis treatments are impractical or contraindicated. The geko™ device is a neuromuscular electrostimulation device which prevents blood stasis in the deep veins of the calf6 by activation of foot and calf muscle pumps via stimulation of the common peroneal nerve.  Weighing just 10g, silent in operation and with no wires or leads, the battery powered geko™ device is a daily disposable device that is self-adhesive and comfortable to wear.



  1. NICE NG89 2018:
  2. Tucker A, et al. Augmentation of venous, arterial and microvascular blood supply in the leg by isometric neuromuscular stimulation via the peroneal nerve. The International journal of angiology: official publication of the International College of Angiology, Inc. 2010 Spring;19(1): e31-7.
  3. Roffe & Natarajan et al.
  4. Dennis M, et al. Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial. Lancet. 2013; 382(9891):516-24.
  5. NICE guidance (MTG19) 2014. Data on file Firstkind Ltd.
  6. Nicolaides A, Griffin M. Measurement of blood flow in the deep veins of the lower limb using the geko™ neuromuscular electro-stimulation device. Journal of International Angiology August 2016-04.