Eliciting preferences of persons with dementia and informal caregivers to support ageing in place in the Netherlands: a protocol for a discrete choice experiment

Introduction Nearly every country across Europe has reformed its long-term care policy to emphasise ageing in…

Cost-effectiveness analysis of probiotic peanut oral immunotherapy (PPOIT) versus placebo in Australian children with peanut allergy alongside a randomised trial

STRENGTHS AND LIMITATIONS OF THIS STUDY This study is the first to conduct a trial-based economic…

Methodological guidelines and publications of benefit-risk assessment for health technology assessment: a scoping review protocol

Introduction Benefit–risk assessment (BRA), also called benefit–harm assessment, is used in multiple phases along a health…

Assessing the risk of COVID-19 reinfection and severe outcomes among individuals with substance use disorders: a retrospective study using real-world electronic health records

STRENGTHS AND LIMITATIONS OF THIS STUDY This study used large-scale electronic health record-based data, which provide…

Effectiveness and safety of nintedanib in prevention of pulmonary fibrosis induced by bleomycin in malignant ovarian germ cell tumour: study protocol for a randomised, double-blind, placebo-controlled trial

STRENGTHS AND LIMITATIONS OF THIS STUDY This trial aims to evaluate the effectiveness and the safety…

Rationale and design of a comparison of angiography-derived fractional flow reserve-guided and intravascular ultrasound-guided intervention strategy for clinical outcomes in patients with coronary artery disease: a randomised controlled trial (FLAVOUR II)

STRENGTHS AND LIMITATIONS OF THIS STUDY This trial is the first randomised controlled trial to compare…

What is the current global health participation and future interest of healthcare students and National Health Service (NHS) staff? A cross-sectional research study of healthcare students and NHS staff in England

Introduction Global health is an academic discipline which ‘places priority on improving health and achieving equity…

Impact of smoking cessation on non-alcoholic fatty liver disease prevalence: a systematic review and meta-analysis

Introduction Non-alcoholic fatty liver disease (NAFLD) is regarded as the hepatic manifestation of metabolic syndrome and…

Measuring the success of programmes of care for people living with dementia: a protocol for consensus building with consumers to develop a set of Core Outcome Measures for Improving Care (COM-IC)

Background and rationale Dementia is a syndrome characterised by cognitive and functional decline, posing unique and…

Effectiveness of social support programmes on loneliness in community-dwelling older adults: study protocol for a meta-analysis of randomised controlled trials

Introduction Loneliness is a distressing psychological experience caused by a personal perception of discrepancies between one’s…